Stopping Xanax suddenly can be risky. If left untreated, benzodiazepine withdrawal can trigger a delirium with hallucinations, changes in consciousness, profound agitation, autonomic instability, seizures, and even death. Doctors always recommend Xanax dosage be gradually tapered or substituting a long-acting medication for a short-acting one – this helps you avoid uncomfortable and potentially dangerous withdrawal effects. Stopping alprazolam suddenly can also cause a Xanax relapse if you feel the need to take Xanax to avoid withdrawal symptoms.
The amount of oxycodone that is safe for you depends on your body’s current exposure to opioids . The amount of oxycodone that is too much for you is relative to how tolerant your body already is to oxycodone, opiates or opioids. Safe dosing levels of oxycodone will also depend upon the type of oxycodone you are taking. Oxycodone in immediate action or controlled release form is available in different doses, and has different actions. Furthermore, as doctors increase doses, they consider a number of different variables, including your age, weight, general health and other medication.. So, how much oxycodone is too much really depends on your specific case.
Amanda, your MEDLINE “rather than PubMed” adds to the confusion of the interface for the content. There is no PubMed search that is not a MEDLINE (+) search unless you use NOT medline[sb] with your search string. The fact that citations from journals that will never be indexed, ., never become a MEDLINE record, are in PubMed is really not a problem if one is clear on this distinction. Searching MEDLINE via a non- PubMed interface is probably a bad idea for an SR unless one includes a “pre-MEDLINE” (aka, PubMed records) search. BTW, if you are unable to define “predatory journal,” how can you warn systematic reviewers about them without introducing bias into the SR process? One can more convincingly argue that journal titles and authors should be blinded to reviewers to avoid this kind of publication bias – the quality of the research is what determines if it’s included in final SR analysis, not the relative prestige of the author or journal in which it is published.