It’s going to be tough to find out. Efforts to map out the metabolic pathways of meandering cannabinoids are hamstrung by their banishment to the DEA’s schedule I list, with rogues like LSD and heroin. Winning federal funding – the lifeblood of basic medical research – to study schedule I drugs the DEA describes as having “no currently accepted medical use” is exceedingly difficult, Whitaker says. The irony that medical marijuana is legal in 20 states and the District of Columbia is hard to miss. Crystal meth and cocaine, schedule II drugs, are easier to study.
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All bets are off the table when high-dose testosterone and its many metabolites are used illegally, such as with anabolic steroid abuse. Strokes, embolisms, and cardiovascular disease are all more likely, as is sudden death, and liver and kidney disease. 44 In women, acne, irreversible deepening of the voice, baldness, increased facial hair, enlarged sex organs, breast reduction, depression, and infertility have all been reported. In adult men that abuse anabolic steroids, acne, baldness, permanent infertility, gynecomastia, loss of libido, erectile dysfunction, testicle shrinkage, and profuse sweating are all reported side effects. Increased testicular cancer hasn't been reported, though. 45,46